A New Chapter in Skin Health Begins
In the ever-evolving world of aesthetic medicine, innovation rarely sleeps. Yet every so often, a treatment arrives that doesn’t just catch attention, it changes the game. Polynucleotides are that game-changer.
At Takroni Clinic, located on 75 New Cavendish Street in London, polynucleotide treatments lead a quiet revolution. Rather than masking age-related changes with fillers or freezing movement with toxins, polynucleotides take a radically different approach: they restore what time and inflammation have worn down, from the inside out.
This is regeneration, not camouflage.
What Do Polynucleotides Do to Your Skin?
Polynucleotides are fragments of DNA derived from highly purified sources, usually salmon or trout. These biologically active molecules are injected into the skin where they act like a cellular whisper, encouraging the body to do what it does best: heal, rebuild, and regenerate.
Here’s what happens beneath the surface:
- Fibroblasts are activated, leading to increased collagen and elastin synthesis.
- Cellular turnover accelerates, smoothing texture and fading pigmentation.
- Inflammation is reduced, calming sensitive, rosacea-prone or post-acne skin.
- Skin hydration is restored by encouraging better water retention at a cellular level.
- Wound repair and DNA repair processes are stimulated, enhancing skin strength.
The result? Skin that not only looks fresher, but functions better, healthier, stronger, and more resilient.
Are Polynucleotides Better Than Anti-Wrinkle Injections?
Let’s get one thing clear: anti-wrinkle injections work. But it’s a muscle relaxant, not a skin treatment. It temporarily blocks the nerve signals that cause dynamic wrinkles, like frown lines or crow’s feet, but it does nothing to improve skin tone, hydration, or structure.
Polynucleotides take a much more comprehensive approach. They stimulate long-term tissue regeneration, support vascular activity, and target the skin, not the muscles beneath it.
Polynucleotides are a biological repair system, whereas anti-wrinkle injections are a surface-level silencer. For patients at Takroni Clinic seeking long-term skin health over temporary aesthetic smoothing, polynucleotides offer an unmatched regenerative route.
What Is Better: Polynucleotides or Microneedling?
Both treatments are powerful. Both stimulate collagen. But they work very differently and can even be combined!
Microneedling triggers a controlled wound-healing response. By creating micro-injuries with tiny needles, it prompts the skin to repair itself, leading to a tighter, more even complexion. It’s brilliant for textural issues, such as scarring, large pores, and fine lines.
Polynucleotides, by contrast, nourish the skin at a cellular level. They do not rely on injury. Instead, they bio-modulate the environment, turning on the skin’s natural healing capabilities without creating trauma.
At Takroni Clinic, these two treatments are often combined for a synergistic effect: microneedling prepares the canvas, and polynucleotides fuel the regeneration.
Are Polynucleotides Better Than Profhilo?
It depends on what your skin needs. Profhilo is a highly concentrated injectable hyaluronic acid that deeply hydrates the skin and slightly lifts it. It’s a hydration-first treatment, great for dull, dry, crepey skin.
But hydration isn’t the same as regeneration.
Polynucleotides stimulate collagen, reduce inflammation, improve vascularity, and restore cellular function. They’re particularly effective for:
- The eye area
- Sagging and fine lines
- Inflammatory skin conditions
- Sun damage and age-related thinning
If Profhilo is the drink your skin needs, polynucleotides are the diet, exercise, and sleep, nourishing it long term.
Who Should Consider Polynucleotide Therapy?
At Takroni Clinic, we recommend polynucleotides to women and men aged 35–75 who are noticing:
- A loss of skin elasticity or firmness
- Thin, crepey, or fragile skin
- Dehydration that topical skincare can’t fix
- Redness, sensitivity, or a history of inflammation
- Delayed wound healing or poor skin recovery
- Early signs of ageing without volume loss
These are patients who want lasting improvements, not fleeting enhancements.
Polynucleotides are also a brilliant post-laser or post-peel treatment, helping to reduce downtime and accelerate healing.
What to Expect From Treatment
Polynucleotides are delivered through a series of small injections, typically using a cannula or fine needle, depending on the area being treated. Common zones include:
- Periorbital (under-eye) area
- Midface and cheeks
- Neck and décolletage
- Back of hands
The treatment is minimally invasive and well tolerated. Mild swelling or redness may occur, but this usually subsides within 24-48 hours.
At Takroni Clinic, we usually recommend three sessions spaced 2-3 weeks apart, with results continuing to develop over several months as your skin remodels itself from within.
Why Choose Takroni Clinic for Polynucleotides in London?
Situated in the heart of Marylebone, Takroni Clinic offers advanced, medical-led aesthetic treatments grounded in anatomy, science, and integrity.
We don’t offer “quick-fix beauty.” We offer intelligent, tailored protocols that honour your unique facial architecture and biology.
Polynucleotide treatments at our London clinic are performed exclusively by medical professionals, using only the most reputable formulations, in a setting that’s calm, clinical, and focused on achieving measurable skin health gains.