Lines and wrinkles develop over time because of muscle movement over time, collagen loss and facial fat volume loss in the face. Some lines in the face can also be related to the sleeping position, over time causing deepening creases on the face. A combination of facial movement, sleeping position, facial fat volume loss and the fat pads dropping in the face over time is responsible for concerns such as: forehead lines, crow’s feet, frown lines, nasolabial folds (nose to mouth lines) and marionette creases (mouth to chin lines); conditions which Takroni Clinic will often recommend for our anti-wrinkle treatment or other interventions such as dermal filler or skin quality treatments to enhance the results.